Anti-CXXC1 antibody (401-660) (STJ28377)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CXXC1 (401-660) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CXXC1 |
| Gene ID | 30827 |
| Uniprot ID | CXXC1_HUMAN |
| Immunogen Region | 401-660 |
| Immunogen Sequence | MKLAANRIYEILPQRIQQWQ QSPCIAEEHGKKLLERIRRE QQSARTRLQEMERRFHELEA IILRAKQQAVREDEESNEGD SDDTDLQIFCVSCGHPINPR VALRHMERCYAKYESQTSFG SMYPTRIEGATRLFCDVYNP QSKTYCKRLQVLCPEHSRDP KVPADEVCGCPLVRDVFELT GDFCRLPKRQCNRHYCWEKL RRAEVDLERVRVWYKLDELF EQERNVRTAMTNRAGLLAL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 401-660 of human CXXC1 (NP_001095124.1). |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | May be regulated by proteolysis. |
| Function | Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG. |
| Protein Name | Cxxc-Type Zinc Finger Protein 1Cpg-Binding ProteinPhd Finger And Cxxc Domain-Containing Protein 1 |
| Database Links | Reactome: R-HSA-381038Reactome: R-HSA-9772755 |
| Cellular Localisation | Nucleus SpeckleNucleusAssociated With EuchromatinDuring MitosisExcluded From Condensed Chromosomes |
| Alternative Antibody Names | Anti-Cxxc-Type Zinc Finger Protein 1 antibodyAnti-Cpg-Binding Protein antibodyAnti-Phd Finger And Cxxc Domain-Containing Protein 1 antibodyAnti-CXXC1 antibodyAnti-CFP1 antibodyAnti-CGBP antibodyAnti-PCCX1 antibodyAnti-PHF18 antibody |
Information sourced from Uniprot.org