| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CXXC1 |
| Gene ID: | 30827 |
| Uniprot ID: | CXXC1_HUMAN |
| Immunogen Region: | 401-660 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 401-660 of human CXXC1 (NP_001095124.1). |
| Immunogen Sequence: | MKLAANRIYEILPQRIQQWQ QSPCIAEEHGKKLLERIRRE QQSARTRLQEMERRFHELEA IILRAKQQAVREDEESNEGD SDDTDLQIFCVSCGHPINPR VALRHMERCYAKYESQTSFG SMYPTRIEGATRLFCDVYNP QSKTYCKRLQVLCPEHSRDP KVPADEVCGCPLVRDVFELT GDFCRLPKRQCNRHYCWEKL RRAEVDLERVRVWYKLDELF EQERNVRTAMTNRAGLLAL |
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | May be regulated by proteolysis. |
| Function | Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG. |
| Protein Name | Cxxc-Type Zinc Finger Protein 1Cpg-Binding ProteinPhd Finger And Cxxc Domain-Containing Protein 1 |
| Database Links | Reactome: R-HSA-381038Reactome: R-HSA-9772755 |
| Cellular Localisation | Nucleus SpeckleNucleusAssociated With EuchromatinDuring MitosisExcluded From Condensed Chromosomes |
| Alternative Antibody Names | Anti-Cxxc-Type Zinc Finger Protein 1 antibodyAnti-Cpg-Binding Protein antibodyAnti-Phd Finger And Cxxc Domain-Containing Protein 1 antibodyAnti-CXXC1 antibodyAnti-CFP1 antibodyAnti-CGBP antibodyAnti-PCCX1 antibodyAnti-PHF18 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and ANKRD52 knockout (KO) 293T cells, using [KO Validated] ANKRD52 Rabbit polyclonal antibody (STJ11100834) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89769/358241/STJ11100834_1__55275.1713122574.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and ANKRD52 knockout (KO) 293T cells, using [KO Validated] ANKRD52 Rabbit polyclonal antibody (STJ11100834) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
