| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S1MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000IF/ICC:1:100-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CXCR5 |
| Gene ID: | 643 |
| Uniprot ID: | CXCR5_HUMAN |
| Immunogen Region: | 273-372 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 273-372 of human CXCR5 (P32302). |
| Immunogen Sequence: | SPYHIVIFLDTLARLKAVDN TCKLNGSLPVAITMCEFLGL AHCCLNPMLYTFAGVKFRSD LSRLLTKLGCTGPASLCQLF PSWRRSSLSESENATSLTTF |
| Tissue Specificity | Expression in mature B-cells and Burkitt lymphoma cells. |
| Function | Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation. |
| Protein Name | C-X-C Chemokine Receptor Type 5Cxc-R5Cxcr-5Burkitt Lymphoma Receptor 1Monocyte-Derived Receptor 15Mdr-15Cd Antigen Cd185 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-C-X-C Chemokine Receptor Type 5 antibodyAnti-Cxc-R5 antibodyAnti-Cxcr-5 antibodyAnti-Burkitt Lymphoma Receptor 1 antibodyAnti-Monocyte-Derived Receptor 15 antibodyAnti-Mdr-15 antibodyAnti-Cd Antigen Cd185 antibodyAnti-CXCR5 antibodyAnti-BLR1 antibodyAnti-MDR15 antibody |
Information sourced from Uniprot.org
