Anti-CXCL17 antibody (1-50 aa) (STJ192061)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein at the amino acid range 1-50
STJ192061
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General Information

Short DescriptionRabbit polyclonal anti-C-X-C motif chemokine 17 (1-50 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman/Rat/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-2000
ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolCXCL17
Gene ID284340
Uniprot IDCXL17_HUMAN
ImmunogenSynthesized peptide derived from part of the human protein at the amino acid range 1-50
Immunogen Region1-50 aa
SpecificityVCC1 Polyclonal Antibody detects endogenous levels of protein.

Additional Info

Post Translational Modifications Likely to undergo an endoproteolytic process to form a four-cysteine-containing mature peptide with a canonical CXC chemokine scaffold after secretion.
Function Chemokine that acts as a chemoattractant for monocytes, macrophages and dendritic cells. Plays a role in angiogenesis and possibly in the development of tumors. Acts as an anti-inflammatory in the stomach. May play a role in the innate defense against infections. Activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions. 4-Cys CXCL17: Seems to exhibit much higher chemoattractant potency on monocytes and macrophages than 6-Cys CXCL17.
Protein Name C-X-C Motif Chemokine 17
6-Cys Cxcl17
Dendritic Cell And Monocyte Chemokine-Like Protein
Dmc
Vegf Coregulated Chemokine 1 Cleaved Into - 4-Cys Cxcl17
Database Links
Cellular Localisation Secreted
Alternative Antibody Names Anti-C-X-C Motif Chemokine 17 antibody
Anti-6-Cys Cxcl17 antibody
Anti-Dendritic Cell And Monocyte Chemokine-Like Protein antibody
Anti-Dmc antibody
Anti-Vegf Coregulated Chemokine 1 Cleaved Into - 4-Cys Cxcl17 antibody
Anti-CXCL17 antibody
Anti-VCC1 antibody
Anti-UNQ473 antibody
Anti-PRO842 antibody

Information sourced from Uniprot.org

Citations

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