| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-CTP synthase 1 (60-109 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CTPS1 |
| Gene ID: | 1503 |
| Uniprot ID: | PYRG1_HUMAN |
| Immunogen Region: | 60-109 aa |
| Specificity: | CTPS Polyclonal Antibody detects endogenous levels of CTPS protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human CTPS at the amino acid range 60-109 |
| Function | This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product, CTP, play a crucial role in the proliferation of activated lymphocytes and therefore in immunity. |
| Protein Name | Ctp Synthase 1Ctp Synthetase 1Utp--Ammonia Ligase 1 |
| Database Links | Reactome: R-HSA-499943 |
| Cellular Localisation | CytoplasmCytosolMainly Cytosolic But When Active Detected In Long Filamentous StructuresCo-Localizes With Tnk2 In The Cytosolic Filaments |
| Alternative Antibody Names | Anti-Ctp Synthase 1 antibodyAnti-Ctp Synthetase 1 antibodyAnti-Utp--Ammonia Ligase 1 antibodyAnti-CTPS1 antibodyAnti-CTPS antibody |
Information sourced from Uniprot.org
