Anti-CTPS1 antibody (60-109 aa) (STJ92518)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human CTPS at the amino acid range 60-109
General Information
| Short Description | Rabbit polyclonal anti-CTP synthase 1 (60-109 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CTPS1 |
| Gene ID | 1503 |
| Uniprot ID | PYRG1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human CTPS at the amino acid range 60-109 |
| Immunogen Region | 60-109 aa |
| Specificity | CTPS Polyclonal Antibody detects endogenous levels of CTPS protein. |
Additional Info
| Function | This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product, CTP, play a crucial role in the proliferation of activated lymphocytes and therefore in immunity. |
| Protein Name | Ctp Synthase 1Ctp Synthetase 1Utp--Ammonia Ligase 1 |
| Database Links | Reactome: R-HSA-499943 |
| Cellular Localisation | CytoplasmCytosolMainly Cytosolic But When Active Detected In Long Filamentous StructuresCo-Localizes With Tnk2 In The Cytosolic Filaments |
| Alternative Antibody Names | Anti-Ctp Synthase 1 antibodyAnti-Ctp Synthetase 1 antibodyAnti-Utp--Ammonia Ligase 1 antibodyAnti-CTPS1 antibodyAnti-CTPS antibody |
Information sourced from Uniprot.org