Anti-CTPS1 antibody (200-300) [S4108RM] (STJ11104108)

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STJ11104108
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Host: Rabbit
Applications: WB/IP/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : S4108RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cells
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CTPS1
Gene ID: 1503
Uniprot ID: PYRG1_HUMAN
Immunogen Region: 200-300
Specificity: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human CTP synthase/CTPS (P17812).
Immunogen Sequence: SVRELRGLGLSPDLVVCRCS NPLDTSVKEKISMFCHVEPE QVICVHDVSSIYRVPLLLEE QGVVDYFLRRLDLPIERQPR KMLMKWKEMADRYDRLLETC S
Tissue Specificity Widely expressed.
Function This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product, CTP, play a crucial role in the proliferation of activated lymphocytes and therefore in immunity.
Protein Name Ctp Synthase 1
Ctp Synthetase 1
Utp--Ammonia Ligase 1
Database Links Reactome: R-HSA-499943
Cellular Localisation Cytoplasm
Cytosol
Mainly Cytosolic But When Active Detected In Long Filamentous Structures
Co-Localizes With Tnk2 In The Cytosolic Filaments
Alternative Antibody Names Anti-Ctp Synthase 1 antibody
Anti-Ctp Synthetase 1 antibody
Anti-Utp--Ammonia Ligase 1 antibody
Anti-CTPS1 antibody
Anti-CTPS antibody

Information sourced from Uniprot.org