• Western blot analysis of extracts of various cell lines, using CTP synthase/CTPS antibody (STJ11104108) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
  • Western blot analysis of extracts of various cell lines, using CTP synthase/CTPS antibody (STJ11104108) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-CTPS1 antibody (200-300) [S4108RM] (STJ11104108)

SKU:
STJ11104108

£146.50 - £639.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Ctp Synthase 1 (200-300) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S4108RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:100-1:500
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CTPS1
Gene ID: 1503
Uniprot ID: PYRG1_HUMAN
Immunogen Region: 200-300
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human CTP synthase/CTPS (P17812).
Immunogen Sequence: SVRELRGLGLSPDLVVCRCS NPLDTSVKEKISMFCHVEPE QVICVHDVSSIYRVPLLLEE QGVVDYFLRRLDLPIERQPR KMLMKWKEMADRYDRLLETC S
Tissue Specificity Widely expressed.
Function This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product, CTP, play a crucial role in the proliferation of activated lymphocytes and therefore in immunity.
Protein Name Ctp Synthase 1
Ctp Synthetase 1
Utp--Ammonia Ligase 1
Database Links Reactome: R-HSA-499943
Cellular Localisation Cytoplasm
Cytosol
Mainly Cytosolic But When Active Detected In Long Filamentous Structures
Co-Localizes With Tnk2 In The Cytosolic Filaments
Alternative Antibody Names Anti-Ctp Synthase 1 antibody
Anti-Ctp Synthetase 1 antibody
Anti-Utp--Ammonia Ligase 1 antibody
Anti-CTPS1 antibody
Anti-CTPS antibody

Information sourced from Uniprot.org

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