Host: |
Mouse |
Applications: |
ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-cTnT (139-152) is suitable for use in ELISA research applications. |
Clonality: |
Monoclonal |
Clone ID: |
3712 |
Conjugation: |
Unconjugated |
Isotype: |
IgG1 |
Formulation: |
50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
Purification: |
Greater than 95% purity |
Concentration: |
5.0 mg/ml (+/-10 %) |
Storage Instruction: |
18 months from manufacturing at 2–8°C. Temperature analysis:-70 °C, 21 days Not Determined (N/D)-20 °C, 14 days OK +4 °C, 14 days OK +35 °C, 14 days OK +45 °C, 7 days OK. Shelf life stability testing at 2–8 °C in the product buffer. |
Association Rate Constant: |
2.1 x 106 1/Ms |
Determination Method: |
SPR analysis (ProteOn XPR36) |
Immunoreactivity: |
80–120 % compared to the reference sample in an FIA test |
Gene Symbol: |
TNNT2 |
Gene ID: |
7139 |
Uniprot ID: |
TNNT2_HUMAN |
Immunogen Region: |
139-152 |
Immunogen: |
Human cardiac troponin T (cTnT) |
Tissue Specificity | Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart. |
Post Translational Modifications | Phosphorylation at Thr-213 by PRKCA induces significant reduction in myofilament calcium sensitivity and actomyosin ATPase activity. |
Function | Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. |
Protein Name | Troponin T - Cardiac MuscleTntcCardiac Muscle Troponin TCtnt |
Database Links | Reactome: R-HSA-390522 |
Alternative Antibody Names | Anti-Troponin T - Cardiac Muscle antibodyAnti-Tntc antibodyAnti-Cardiac Muscle Troponin T antibodyAnti-Ctnt antibodyAnti-TNNT2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance