| Host: | Goat |
| Applications: | Pep-ELISA/IF/IHC |
| Reactivity: | Human/Mouse/Rat/Dog/Pig/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-CTGF (Internal) is suitable for use in ELISA, Immunofluorescence and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.IHC: Paraffin embedded Rat Liver. Recommended concentration: 6-8µg/ml.IF: Strong expression of the protein seen in the cytoplasm/membrane of NIH3T3 and HepG2 cells. Recommended concen |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | CCN2 |
| Gene ID: | 1490 |
| Uniprot ID: | CCN2_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_001892.1 |
| Specificity: | Immunizing peptide overlaps disulphide bond |
| Immunogen Sequence: | TLPVEFKCPDGE |
| Function | Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. |
| Protein Name | Ccn Family Member 2Cellular Communication Network Factor 2Connective Tissue Growth FactorHypertrophic Chondrocyte-Specific Protein 24Insulin-Like Growth Factor-Binding Protein 8Ibp-8Igf-Binding Protein 8Igfbp-8 |
| Database Links | Reactome: R-HSA-2032785Reactome: R-HSA-8951671 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Ccn Family Member 2 antibodyAnti-Cellular Communication Network Factor 2 antibodyAnti-Connective Tissue Growth Factor antibodyAnti-Hypertrophic Chondrocyte-Specific Protein 24 antibodyAnti-Insulin-Like Growth Factor-Binding Protein 8 antibodyAnti-Ibp-8 antibodyAnti-Igf-Binding Protein 8 antibodyAnti-Igfbp-8 antibodyAnti-CCN2 antibodyAnti-CTGF antibodyAnti-HCS24 antibodyAnti-IGFBP8 antibody |
Information sourced from Uniprot.org
