Anti-CTDSP1, Biotinylated antibody (Internal) {Biotin} (STJ73195)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationBiotin
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-CTDSP1, Biotinylated (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 30kDa band observed in Mouse Testis lysates (calculated MW of 29.3kDa according to Mouse NP_694728.1). See non-biotinylated parental product's datasheet for further QC data. Rec |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | CTDSP1 |
| Gene ID | 58190 |
| Uniprot ID | CTDS1_HUMAN |
| Accession Number | NP_067021.1; NP_872580.1; NP_001193807.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | EAKAQDSDKIC. |
| Specificity | This antibody is expected to recognize all three reported isoforms (NP_067021.1; NP_872580.1; NP_001193807.1). |
Additional Info
| Function | Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. |
| Protein Name | Carboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 1Nuclear Lim Interactor-Interacting Factor 3Nli-IfNli-Interacting Factor 3Small C-Terminal Domain Phosphatase 1Scp1Small Ctd Phosphatase 1 |
| Cellular Localisation | NucleusColocalizes With Rna Polymerase Ii |
| Alternative Antibody Names | Anti-Carboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 1 antibodyAnti-Nuclear Lim Interactor-Interacting Factor 3 antibodyAnti-Nli-If antibodyAnti-Nli-Interacting Factor 3 antibodyAnti-Small C-Terminal Domain Phosphatase 1 antibodyAnti-Scp1 antibodyAnti-Small Ctd Phosphatase 1 antibodyAnti-CTDSP1 antibodyAnti-NIF3 antibodyAnti-NLIIF antibodyAnti-SCP1 antibody |
Information sourced from Uniprot.org