| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CST6 (29-149) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CST6 |
| Gene ID: |
1474 |
| Uniprot ID: |
CYTM_HUMAN |
| Immunogen Region: |
29-149 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 29-149 of human CST6 (NP_001314.1). |
| Immunogen Sequence: |
RPQERMVGELRDLSPDDPQV QKAAQAAVASYNMGSNSIYY FRDTHIIKAQSQLVAGIKYF LTMEMGSTDCRKTRVTGDHV DLTTCPLAAGAQQEKLRCDF EVLVVPWQNSSQLLKHNCVQ M |
| Tissue Specificity | Restricted to the stratum granulosum of normal skin, the stratum granulosum/spinosum of psoriatic skin, and the secretory coils of eccrine sweat glands. Low expression levels are found in the nasal cavity. |
| Post Translational Modifications | Substrate for transglutaminases. Acts as an acyl acceptor but not as an acyl donor. |
| Function | High affinity inhibitor for cathepsin L, cathepsin L2 (cathepsin V), and legumain. Involved in the regulation of epidermal cornification, and hair follicle morphogenesis and maintenance. |
| Protein Name | Cystatin-MCystatin-6Cystatin-E |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Cystatin-M antibodyAnti-Cystatin-6 antibodyAnti-Cystatin-E antibodyAnti-CST6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
