| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:5000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KAT14 |
| Gene ID: | 57325 |
| Uniprot ID: | CSR2B_HUMAN |
| Immunogen Region: | 523-782 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 523-782 of human CSRP2BP (NP_065397.3). |
| Immunogen Sequence: | DGIYGAKEGGISRLPAGQAT YRTTCQDFRILDRYQTSLPS RKGFRHQTTKFLYRLVGSED MAVDQSIVSPYTSRILKPYI RRDYETKPPKLQLLSQIRSH LHRSDPHWTPEPDAPLDYCY VRPNHIPTINSMCQEFFWPG IDLSECLQYPDFSVVVLYKK VIIAFGFMVPDVKYNEAYIS FLFVHPEWRRAGIATFMIYH LIQTCMGKDVTLHVSASNPA MLLYQKFGFKTEEYVLDFY |
| Tissue Specificity | Expressed in skeletal muscle, heart, lung, placenta, brain, liver, pancreas and kidney. High expression in skeletal muscle and heart. Lower expression in lung. |
| Function | Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. May function as a scaffold for the ATAC complex to promote ATAC complex stability. Has also weak histone acetyltransferase activity toward histone H4. Required for the normal progression through G1 and G2/M phases of the cell cycle. |
| Protein Name | Cysteine-Rich Protein 2-Binding ProteinCsrp2-Binding ProteinAda2a-Containing Complex Subunit 2Atac2Crp2-Binding PartnerCrp2bpLysine Acetyltransferase 14 |
| Database Links | Reactome: R-HSA-3214847Reactome: R-HSA-9772755 |
| Cellular Localisation | NucleusCytoplasmMainly Nuclear |
| Alternative Antibody Names | Anti-Cysteine-Rich Protein 2-Binding Protein antibodyAnti-Csrp2-Binding Protein antibodyAnti-Ada2a-Containing Complex Subunit 2 antibodyAnti-Atac2 antibodyAnti-Crp2-Binding Partner antibodyAnti-Crp2bp antibodyAnti-Lysine Acetyltransferase 14 antibodyAnti-KAT14 antibodyAnti-CSRP2BP antibody |
Information sourced from Uniprot.org