| Host: |
Rabbit |
| Applications: |
ELISA |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
CSF3R |
| Gene ID: |
1441 |
| Uniprot ID: |
CSF3R_HUMAN |
| Immunogen Region: |
30-290 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 30-290 of human CSF3R (NP_000751.1). |
| Immunogen Sequence: |
SVSAPIVHLGDPITASCIIK QNCSHLDPEPQILWRLGAEL QPGGRQQRLSDGTQESIITL PHLNHTQAFLSCCLNWGNSL QILDQVELRAGYPPAIPHNL SCLMNLTTSSLICQWEPGPE THLPTSFTLKSFKSRGNCQT QGDSILDCVPKDGQSHCCIP RKHLLLYQNMGIWVQAENAL GTSMSPQLCLDPMDVVKLEP PMLRTMDPSPEAAPPQAGCL QLCWEPWQPGLHINQKCEL |
| Tissue Specificity | One or several isoforms have been found in myelogenous leukemia cell line KG-1, leukemia U-937 cell line, in bone marrow cells, placenta, and peripheral blood granulocytes. Isoform GCSFR-2 is found only in leukemia U-937 cells. Isoform GCSFR-3 is highly expressed in placenta. |
| Post Translational Modifications | N-glycosylated. |
| Function | Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differentiation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface. |
| Protein Name | Granulocyte Colony-Stimulating Factor ReceptorG-Csf ReceptorG-Csf-RCd Antigen Cd114 |
| Database Links | Reactome: R-HSA-449836Reactome: R-HSA-9616222Reactome: R-HSA-9674555Reactome: R-HSA-9705462 |
| Cellular Localisation | Isoform 2: SecretedCell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Granulocyte Colony-Stimulating Factor Receptor antibodyAnti-G-Csf Receptor antibodyAnti-G-Csf-R antibodyAnti-Cd Antigen Cd114 antibodyAnti-CSF3R antibodyAnti-GCSFR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
