Anti-CRYZ antibody (1-329) (STJ114723)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CRYZ (1-329) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CRYZ |
| Gene ID | 1429 |
| Uniprot ID | QOR_HUMAN |
| Immunogen Region | 1-329 |
| Immunogen Sequence | MATGQKLMRAVRVFEFGGPE VLKLRSDIAVPIPKDHQVLI KVHACGVNPVETYIRSGTYS RKPLLPYTPGSDVAGVIEAV GDNASAFKKGDRVFTSSTIS GGYAEYALAADHTVYKLPEK LDFKQGAAIGIPYFTAYRAL IHSACVKAGESVLVHGASGG VGLAACQIARAYGLKILGTA GTEEGQKIVLQNGAHEVFNH REVNYIDKIKKYVGEKGIDI IIEMLANVNLSKDLSLLSH |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-329 of human CRYZ (NP_001123514.1). |
Additional Info
| Tissue Specificity | Only very low amounts in the lens. |
| Function | Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding. |
| Protein Name | Quinone OxidoreductaseNadph -Quinone ReductaseZeta-Crystallin |
| Database Links | |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Quinone Oxidoreductase antibodyAnti-Nadph -Quinone Reductase antibodyAnti-Zeta-Crystallin antibodyAnti-CRYZ antibody |
Information sourced from Uniprot.org