| Short Description : | Rabbit polyclonal CRX (100-200) antibody for use in WB, IF, ICC and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CRX |
| Gene ID: | 1406 |
| Uniprot ID: | CRX_HUMAN |
| Immunogen Region: | 100-200 |
| Immunogen Sequence: | QQKQQQQPPGGQAKARPAKR KAGTSPRPSTDVCPDPLGIS DSYSPPLPGPSGSPTTAVAT VSIWSPASESPLPEAQRAGL VASGPSLTSAPYAMTYAPAS A |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CRX (NP_000545.1). |
| Tissue Specificity | Retina. |
| Function | Transcription factor that binds and transactivates the sequence 5'-TAATCCA-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors. |
| Protein Name | Cone-Rod Homeobox Protein |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Cone-Rod Homeobox Protein antibodyAnti-CRX antibodyAnti-CORD2 antibody |
Information sourced from Uniprot.org
