| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CRH |
| Gene ID: | 1392 |
| Uniprot ID: | CRF_HUMAN |
| Immunogen Region: | 25-194 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-194 of human CRH (NP_000747.1). |
| Immunogen Sequence: | LLSRGPVPGARQAPQHPQPL DFFQPPPQSEQPQQPQARPV LLRMGEEYFLRLGNLNKSPA APLSPASSLLAGGSGSRPSP EQATANFFRVLLQQLLLPRR SLDSPAALAERGARNALGGH QEAPERERRSEEPPISLDLT FHLLREVLEMARAEQLAQQA HSNRKLMEII |
| Tissue Specificity | Produced by the hypothalamus and placenta. |
| Function | Hormone regulating the release of corticotropin from pituitary gland. Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile. |
| Protein Name | CorticoliberinCorticotropin-Releasing FactorCrfCorticotropin-Releasing Hormone |
| Database Links | Reactome: R-HSA-373080Reactome: R-HSA-418555Reactome: R-HSA-9022702 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Corticoliberin antibodyAnti-Corticotropin-Releasing Factor antibodyAnti-Crf antibodyAnti-Corticotropin-Releasing Hormone antibodyAnti-CRH antibody |
Information sourced from Uniprot.org