| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC |
| Reactivity: | Human/Mouse/Rat/Dog/Pig/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-Creatine transporter 1/SLC6A8 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:8000.WB: Approx 70kDa band observed in Mouse Heart lysates (calculated MW of 71.0kDa according to Mouse NP_598748.1). Recommended concentration: 0.1-0.3µg/ml. Primary incubation was 1 hour. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | SLC6A8 |
| Gene ID: | 6535 |
| Uniprot ID: | SC6A8_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_005620.1; NP_001136277.1; NP_001136278.1 |
| Specificity: | This antibody is expected to recognize all reported isoforms (NP_005620.1; NP_001136277.1; NP_001136278.1). |
| Immunogen Sequence: | ASLANLTCDQLADRR |
| Post Translational Modifications | Glycosylated. |
| Function | Creatine:sodium symporter which mediates the uptake of creatine. Plays an important role in supplying creatine to the brain via the blood-brain barrier. |
| Protein Name | Sodium- And Chloride-Dependent Creatine Transporter 1Ct1Creatine Transporter 1Solute Carrier Family 6 Member 8 |
| Database Links | Reactome: R-HSA-71288 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinApical Cell Membrane |
| Alternative Antibody Names | Anti-Sodium- And Chloride-Dependent Creatine Transporter 1 antibodyAnti-Ct1 antibodyAnti-Creatine Transporter 1 antibodyAnti-Solute Carrier Family 6 Member 8 antibodyAnti-SLC6A8 antibody |
Information sourced from Uniprot.org