| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CRB1 (28-133) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CRB1 |
| Gene ID: |
23418 |
| Uniprot ID: |
CRUM1_HUMAN |
| Immunogen Region: |
28-133 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 28-133 of human CRB1 (NP_957705.1). |
| Immunogen Sequence: |
NKNNTRCLSNSCQNNSTCKD FSKDNDCSCSDTANNLDKDC DNMKDPCFSNPCQGSATCVN TPGERSFLCKCPPGYSGTIC ETTIGSCGKNSCQHGGICHQ DPIYPV |
| Tissue Specificity | Preferential expression in retina, also expressed in brain, testis, fetal brain and fetal eye. Expressed at the outer limiting membrane and apical to adherens junctions in the retina. |
| Post Translational Modifications | Extensively glycosylated. |
| Function | Plays a role in photoreceptor morphogenesis in the retina. May maintain cell polarization and adhesion. |
| Protein Name | Protein Crumbs Homolog 1 |
| Cellular Localisation | Isoform 1: Apical Cell MembraneSingle-Pass Type I Membrane ProteinSecretedCell ProjectionCiliumPhotoreceptor Outer SegmentPhotoreceptor Inner SegmentIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Protein Crumbs Homolog 1 antibodyAnti-CRB1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
