| Tissue Specificity | Retina and pineal gland. Not present in photoreceptor cells but is expressed abundantly in the adjacent retinal pigment epithelium (RPE) and in the Mueller glial cells of the retina. |
| Function | Soluble retinoid carrier essential the proper function of both rod and cone photoreceptors. Participates in the regeneration of active 11-cis-retinol and 11-cis-retinaldehyde, from the inactive 11-trans products of the rhodopsin photocycle and in the de novo synthesis of these retinoids from 11-trans metabolic precursors. The cycling of retinoids between photoreceptor and adjacent pigment epithelium cells is known as the 'visual cycle'. |
| Protein Name | Retinaldehyde-Binding Protein 1Cellular Retinaldehyde-Binding Protein |
| Database Links | Reactome: R-HSA-2187335Reactome: R-HSA-2453902Reactome: R-HSA-9918438 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Retinaldehyde-Binding Protein 1 antibodyAnti-Cellular Retinaldehyde-Binding Protein antibodyAnti-RLBP1 antibodyAnti-CRALBP antibody |
Information sourced from Uniprot.org
