| Host: | Mouse |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-CRABP2 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | ZN176 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Purification: | Affinity Chromatography |
| Concentration: | 0.5-1.0 mg/mL |
| Dilution Range: | IHC 1:50-1:100 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | CRABP2 |
| Gene ID: | 1382 |
| Uniprot ID: | RABP2_HUMAN |
| Immunogen: | Full length human recombinant protein of human CRABP2 (NP_001869) produced in E.coli. |
| Post Translational Modifications | Sumoylated in response to retinoic acid binding, sumoylation is critical for dissociation from ER and subsequent nuclear translocation. |
| Function | Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors. |
| Protein Name | Cellular Retinoic Acid-Binding Protein 2Cellular Retinoic Acid-Binding Protein IiCrabp-Ii |
| Database Links | Reactome: R-HSA-5362517 |
| Cellular Localisation | CytoplasmEndoplasmic ReticulumNucleusUpon Ligand BindingA Conformation Change Exposes A Nuclear Localization Motif And The Protein Is Transported Into The Nucleus |
| Alternative Antibody Names | Anti-Cellular Retinoic Acid-Binding Protein 2 antibodyAnti-Cellular Retinoic Acid-Binding Protein Ii antibodyAnti-Crabp-Ii antibodyAnti-CRABP2 antibody |
Information sourced from Uniprot.org
