| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:100-1:500IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CPT2 |
| Gene ID: | 1376 |
| Uniprot ID: | CPT2_HUMAN |
| Immunogen Region: | 420-658 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 420-658 of human CPT2 (NP_000089.1). |
| Immunogen Sequence: | TDALKTGITAAKEKFDATMK TLTIDCVQFQRGGKEFLKKQ KLSPDAVAQLAFQMAFLRQY GQTVATYESCSTAAFKHGRT ETIRPASVYTKRCSEAFVRE PSRHSAGELQQMMVECSKYH GQLTKEAAMGQGFDRHLFAL RHLAAAKGIILPELYLDPAY GQINHNVLSTSTLSSPAVNL GGFAPVVSDGFGVGYAVHDN WIGCNVSSYPGRNAREFLQC VEKALEDMFDALEGKSIKS |
| Function | Involved in the intramitochondrial synthesis of acylcarnitines from accumulated acyl-CoA metabolites. Reconverts acylcarnitines back into the respective acyl-CoA esters that can then undergo beta-oxidation, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Active with medium (C8-C12) and long-chain (C14-C18) acyl-CoA esters. |
| Protein Name | Carnitine O-Palmitoyltransferase 2 - MitochondrialCarnitine Palmitoyltransferase IiCpt Ii |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-200425 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinMatrix Side |
| Alternative Antibody Names | Anti-Carnitine O-Palmitoyltransferase 2 - Mitochondrial antibodyAnti-Carnitine Palmitoyltransferase Ii antibodyAnti-Cpt Ii antibodyAnti-CPT2 antibodyAnti-CPT1 antibody |
Information sourced from Uniprot.org