| Host: | Goat |
| Applications: | Pep-ELISA/IHC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-CPT1B-Isoform 1 (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Preliminary experiments gave no signal but low background in human kidney and HepG2 lysates at up to 1µg/ml. We would appreciate any feedback from people in the field-have any results |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | CPT1B |
| Gene ID: | 1375 |
| Uniprot ID: | CPT1B_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_689452.1; NP_689451.1; NP_004368.1; NP_001138609.1; NP_001138607.1; NP_001138606.1; NP_001138608.1 |
| Specificity: | This antibody is expected to recognise human isoforms a (NP_689452.1; NP_689451.1; NP_004368.1; NP_001138609.1; NP_001138607.1) , isoform c (NP_001138606.1) and isoform d (NP_001138608.1). |
| Immunogen Sequence: | DIADLFQVPKAYS |
| Function | Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. |
| Protein Name | Carnitine O-Palmitoyltransferase 1 - Muscle IsoformCpt1-MCarnitine O-Palmitoyltransferase I - Muscle IsoformCpt ICpti-MCarnitine Palmitoyltransferase 1bCarnitine Palmitoyltransferase I-Like Protein |
| Database Links | Reactome: R-HSA-200425Reactome: R-HSA-5362517 |
| Cellular Localisation | Mitochondrion Outer MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Carnitine O-Palmitoyltransferase 1 - Muscle Isoform antibodyAnti-Cpt1-M antibodyAnti-Carnitine O-Palmitoyltransferase I - Muscle Isoform antibodyAnti-Cpt I antibodyAnti-Cpti-M antibodyAnti-Carnitine Palmitoyltransferase 1b antibodyAnti-Carnitine Palmitoyltransferase I-Like Protein antibodyAnti-CPT1B antibodyAnti-KIAA1670 antibody |
Information sourced from Uniprot.org