| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CPSF2 |
| Gene ID: | 53981 |
| Uniprot ID: | CPSF2_HUMAN |
| Immunogen Region: | 450-700 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 450-700 of human CPSF2 (NP_059133.1). |
| Immunogen Sequence: | KGSFFKQAKKSYPMFPAPEE RIKWDEYGEIIKPEDFLVPE LQATEEEKSKLESGLTNGDE PMDQDLSDVPTKCISTTESI EIKARVTYIDYEGRSDGDSI KKIINQMKPRQLIIVHGPPE ASQDLAECCRAFGGKDIKVY MPKLHETVDATSETHIYQVR LKDSLVSSLQFCKAKDAELA WIDGVLDMRVSKVDTGVILE EGELKDDGEDSEMQVEAPSD SSVIAQQKAMKSLFGDDEK |
| Function | Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing. |
| Protein Name | Cleavage And Polyadenylation Specificity Factor Subunit 2Cleavage And Polyadenylation Specificity Factor 100 Kda SubunitCpsf 100 Kda Subunit |
| Database Links | Reactome: R-HSA-159231Reactome: R-HSA-72187Reactome: R-HSA-72203Reactome: R-HSA-73856Reactome: R-HSA-77595 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Cleavage And Polyadenylation Specificity Factor Subunit 2 antibodyAnti-Cleavage And Polyadenylation Specificity Factor 100 Kda Subunit antibodyAnti-Cpsf 100 Kda Subunit antibodyAnti-CPSF2 antibodyAnti-CPSF100 antibodyAnti-KIAA1367 antibody |
Information sourced from Uniprot.org