| Post Translational Modifications | The N-terminus is blocked. |
| Function | Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction. May play a role in eye morphogenesis and the development of retinal ganglion cell projections to the midbrain. |
| Protein Name | Cleavage And Polyadenylation Specificity Factor Subunit 1Cleavage And Polyadenylation Specificity Factor 160 Kda SubunitCpsf 160 Kda Subunit |
| Database Links | Reactome: R-HSA-159231Reactome: R-HSA-6784531Reactome: R-HSA-72187Reactome: R-HSA-72203Reactome: R-HSA-73856Reactome: R-HSA-77595 |
| Cellular Localisation | NucleusNucleoplasm |
| Alternative Antibody Names | Anti-Cleavage And Polyadenylation Specificity Factor Subunit 1 antibodyAnti-Cleavage And Polyadenylation Specificity Factor 160 Kda Subunit antibodyAnti-Cpsf 160 Kda Subunit antibodyAnti-CPSF1 antibodyAnti-CPSF160 antibody |
Information sourced from Uniprot.org
