| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:100-1:500IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CPM |
| Gene ID: | 1368 |
| Uniprot ID: | CBPM_HUMAN |
| Immunogen Region: | 204-443 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 204-443 of human CPM (NP_001005502.1). |
| Immunogen Sequence: | VQATGALYSRSLTPDDDVFQ YLAHTYASRNPNMKKGDECK NKMNFPNGVTNGYSWYPLQG GMQDYNYIWAQCFEITLELS CCKYPREEKLPSFWNNNKAS LIEYIKQVHLGVKGQVFDQN GNPLPNVIVEVQDRKHICPY RTNKYGEYYLLLLPGSYIIN VTVPGHDPHITKVIIPEKSQ NFSALKKDILLPFQGQLDSI PVSNPSCPMIPLYRNLPDHS AATKPSLFLFLVSLLHIFF |
| Function | Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins. |
| Protein Name | Carboxypeptidase MCpm |
| Database Links | Reactome: R-HSA-163125 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Carboxypeptidase M antibodyAnti-Cpm antibodyAnti-CPM antibody |
Information sourced from Uniprot.org