| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Complexin-2 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CPLX2 |
| Gene ID: | 10814 |
| Uniprot ID: | CPLX2_HUMAN |
| Specificity: | This antibody detects endogenous levels of CPLX2 at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human CPLX2 |
| Function | Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles. Also involved in mast cell exocytosis. |
| Protein Name | Complexin-2 Complexin Ii Cpx Ii Synaphin-1 |
| Cellular Localisation | Cytoplasm Cytosol Presynapse Nucleus Perikaryon Translocated From The Perikaryon To The Presynaptic Terminals During Maturation Of Neuronal Cells In Mast Cells Cytosol And Nucleus Becomes Enriched Near Plasma Membrane Following Stimulation |
| Alternative Antibody Names | Anti-Complexin-2 antibody Anti-Complexin Ii antibody Anti-Cpx Ii antibody Anti-Synaphin-1 antibody Anti-CPLX2 antibody |
Information sourced from Uniprot.org