| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Carboxypeptidase B2 (321-370 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:40000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CPB2 |
| Gene ID: | 1361 |
| Uniprot ID: | CBPB2_HUMAN |
| Immunogen Region: | 321-370 aa |
| Specificity: | TAFI Polyclonal Antibody detects endogenous levels of TAFI protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human CPB2 at the amino acid range 321-370 |
| Post Translational Modifications | N-glycosylated. N-glycan at Asn-108: Hex5HexNAc4. |
| Function | Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. |
| Protein Name | Carboxypeptidase B2Carboxypeptidase UCpuPlasma Carboxypeptidase BPcpbThrombin-Activable Fibrinolysis InhibitorTafi |
| Database Links | Reactome: R-HSA-2022377Reactome: R-HSA-977606 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Carboxypeptidase B2 antibodyAnti-Carboxypeptidase U antibodyAnti-Cpu antibodyAnti-Plasma Carboxypeptidase B antibodyAnti-Pcpb antibodyAnti-Thrombin-Activable Fibrinolysis Inhibitor antibodyAnti-Tafi antibodyAnti-CPB2 antibody |
Information sourced from Uniprot.org