Anti-COX17 antibody (1-50 aa) (STJ92436)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human COX17 at the amino acid range 1-50
General Information
| Short Description | Rabbit polyclonal anti-Cytochrome c oxidase copper chaperone (1-50 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:5000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | COX17 |
| Gene ID | 10063 |
| Uniprot ID | COX17_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human COX17 at the amino acid range 1-50 |
| Immunogen Region | 1-50 aa |
| Specificity | COX17 Polyclonal Antibody detects endogenous levels of COX17 protein. |
Additional Info
| Post Translational Modifications | Acetylation by KAT8 promotes assembly of the mitochondrial respiratory chain complex IV (CIV). |
| Function | Copper metallochaperone essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Binds two copper ions and delivers them to the metallochaperone SCO1 which transports the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2). |
| Protein Name | Cytochrome C Oxidase Copper Chaperone |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-9864848 |
| Cellular Localisation | Mitochondrion Intermembrane SpaceCytoplasm |
| Alternative Antibody Names | Anti-Cytochrome C Oxidase Copper Chaperone antibodyAnti-COX17 antibody |
Information sourced from Uniprot.org