| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Cytochrome c oxidase copper chaperone (1-50 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:5000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | COX17 |
| Gene ID: | 10063 |
| Uniprot ID: | COX17_HUMAN |
| Immunogen Region: | 1-50 aa |
| Specificity: | COX17 Polyclonal Antibody detects endogenous levels of COX17 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human COX17 at the amino acid range 1-50 |
| Post Translational Modifications | Acetylation by KAT8 promotes assembly of the mitochondrial respiratory chain complex IV (CIV). |
| Function | Copper metallochaperone essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Binds two copper ions and delivers them to the metallochaperone SCO1 which transports the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2). |
| Protein Name | Cytochrome C Oxidase Copper Chaperone |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-9864848 |
| Cellular Localisation | Mitochondrion Intermembrane SpaceCytoplasm |
| Alternative Antibody Names | Anti-Cytochrome C Oxidase Copper Chaperone antibodyAnti-COX17 antibody |
Information sourced from Uniprot.org
