• Immunohistochemistry analysis of paraffin-embedded human brain tissue, using COX15 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-COX15 antibody (181-230 aa) (STJ92435)

SKU:
STJ92435

£48.00 - £252.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Cytochrome c oxidase assembly protein COX15 homolog (181-230 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:5000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: COX15
Gene ID: 1355
Uniprot ID: COX15_HUMAN
Immunogen Region: 181-230 aa
Specificity: COX15 Polyclonal Antibody detects endogenous levels of COX15 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human COX15 at the amino acid range 181-230
Function Catalyzes the second reaction in the biosynthesis of heme A, a prosthetic group of mitochondrial cytochrome c oxidase (CcO). Heme A is synthesized from heme B by two sequential enzymatic reactions catalyzed by heme O synthase (HOS) and heme A synthase (HAS). HAS catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8, in a reaction that involves matrix ferredoxin and ferredoxin reductase. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
Protein Name Heme A Synthase Cox15
Has
Cytochrome C Oxidase Assembly Protein Cox15 Homolog
Database Links Reactome: R-HSA-189451
Reactome: R-HSA-9864848
Cellular Localisation Mitochondrion Inner Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Heme A Synthase Cox15 antibody
Anti-Has antibody
Anti-Cytochrome C Oxidase Assembly Protein Cox15 Homolog antibody
Anti-COX15 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance