| Function | Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity is still unclear: may act as a protein kinase that mediates phosphorylation of COQ3. According to other reports, acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway, as suggested by its ability to bind coenzyme Q lipid intermediates. However, the small molecule kinase activity was not confirmed by another publication. Shows an unusual selectivity for binding ADP over ATP. |
| Protein Name | Atypical Kinase Coq8a - MitochondrialChaperone Activity Of Bc1 Complex-LikeChaperone-Abc1-LikeCoenzyme Q Protein 8aAarf Domain-Containing Protein Kinase 3 |
| Database Links | Reactome: R-HSA-2142789 |
| Cellular Localisation | Mitochondrion MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Atypical Kinase Coq8a - Mitochondrial antibodyAnti-Chaperone Activity Of Bc1 Complex-Like antibodyAnti-Chaperone-Abc1-Like antibodyAnti-Coenzyme Q Protein 8a antibodyAnti-Aarf Domain-Containing Protein Kinase 3 antibodyAnti-COQ8A antibodyAnti-ADCK3 antibodyAnti-CABC1 antibodyAnti-PP265 antibody |
Information sourced from Uniprot.org
