• Western blot analysis of the lysates from Jurkat cells using COMT antibody.
  • Western blot analysis of lysates from HUVEC and HepG2 cells, using COMT Antibody. The lane on the right is blocked with the synthesized peptide.

Anti-COMT antibody (61-110 aa) (STJ92405)

SKU:
STJ92405

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Catechol O-methyltransferase (61-110 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: COMT
Gene ID: 1312
Uniprot ID: COMT_HUMAN
Immunogen Region: 61-110 aa
Specificity: COMT Polyclonal Antibody detects endogenous levels of COMT protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human COMT at the amino acid range 61-110
Post Translational Modifications The N-terminus is blocked.
Function Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.
Protein Name Catechol O-Methyltransferase
Database Links Reactome: R-HSA-156581
Reactome: R-HSA-379397
Reactome: R-HSA-379398
Reactome: R-HSA-9679191
Cellular Localisation Isoform Soluble: Cytoplasm
Isoform Membrane-Bound: Cell Membrane
Single-Pass Type Ii Membrane Protein
Extracellular Side
Alternative Antibody Names Anti-Catechol O-Methyltransferase antibody
Anti-COMT antibody

Information sourced from Uniprot.org

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