| Host: | Rabbit |
| Applications: | IHC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Comm Domain-Containing Protein 6 is suitable for use in Immunohistochemistry and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Purification: | Antigen affinity purification |
| Concentration: | 1.4 mg/mL |
| Dilution Range: | IHC 1:30-1:150 |
| Storage Instruction: | Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Gene Symbol: | COMMD6 |
| Gene ID: | 170622 |
| Uniprot ID: | COMD6_HUMAN |
| Immunogen: | Full length fusion protein |
| Tissue Specificity | Ubiquitous. Expressed in brain, heart, skeletal muscle, lung, pancreas, liver, kidney, small intestine and placenta. |
| Function | May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Down-regulates activation of NF-kappa-B. Inhibits TNF-induced NFKB1 activation. |
| Protein Name | Comm Domain-Containing Protein 6 |
| Database Links | Reactome: R-HSA-8951664 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Comm Domain-Containing Protein 6 antibodyAnti-COMMD6 antibodyAnti-MSTP076 antibody |
Information sourced from Uniprot.org