| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-COMM domain-containing protein 3 (24-74 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | COMMD3 |
| Gene ID: | 23412 |
| Uniprot ID: | COMD3_HUMAN |
| Immunogen Region: | 24-74 aa |
| Specificity: | This antibody detects endogenous levels of COMD3 at Human/Mouse/Rat |
| Immunogen: | Synthesized peptide derived from the human COMD3 at the amino acid range 24-74 |
| Function | May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B. Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits. |
| Protein Name | Comm Domain-Containing Protein 3 Protein Bup Protein Pil |
| Database Links | Reactome: R-HSA-6798695 Reactome: R-HSA-8951664 |
| Cellular Localisation | Cytoplasm Nucleus |
| Alternative Antibody Names | Anti-Comm Domain-Containing Protein 3 antibody Anti-Protein Bup antibody Anti-Protein Pil antibody Anti-COMMD3 antibody Anti-BUP antibody Anti-C10orf8 antibody |
Information sourced from Uniprot.org