Host: |
Rabbit |
Applications: |
IHC/WB |
Reactivity: |
Rat/Mouse/Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Colon carcinoma laminin binding protein (50-100 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Lyophilised |
Purification: |
IgG purified |
Dilution Range: |
IHC, WB. A dilution of 1:3000 is recommended for WB and 1:1000 for OHC-P. The optimal dilution should be determined by the end user. |
Storage Instruction: |
Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Gene Symbol: |
RPSA |
Gene ID: |
3921 |
Uniprot ID: |
RSSA_HUMAN |
Immunogen Region: |
50-100 aa |
Specificity: |
Specific for 40S ribosomal protein SA |
Immunogen: |
A synthetic peptide aa region 50-100 of human 40S ribosomal protein SA conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse. |
Function | Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. (Microbial infection) Acts as a receptor for the Adeno-associated viruses 2,3,8 and 9. (Microbial infection) Acts as a receptor for the Dengue virus. (Microbial infection) Acts as a receptor for the Sindbis virus. (Microbial infection) Acts as a receptor for the Venezuelan equine encephalitis virus. (Microbial infection) Acts as a receptor for the pathogenic prion protein. (Microbial infection) Acts as a receptor for bacteria. |
Protein Name | Small Ribosomal Subunit Protein Us237 Kda Laminin Receptor Precursor37lrp37/67 Kda Laminin ReceptorLrp/Lr40s Ribosomal Protein Sa67 Kda Laminin Receptor67lrColon Carcinoma Laminin-Binding ProteinLaminin Receptor 1LamrLaminin-Binding Protein Precursor P40Lbp/P40Multidrug Resistance-Associated Protein Mgr1-AgNem/1chd4 |
Database Links | Reactome: R-HSA-156827Reactome: R-HSA-156902Reactome: R-HSA-1799339Reactome: R-HSA-192823Reactome: R-HSA-2408557Reactome: R-HSA-6791226Reactome: R-HSA-72649Reactome: R-HSA-72689Reactome: R-HSA-72695Reactome: R-HSA-72702Reactome: R-HSA-72706Reactome: R-HSA-72764Reactome: R-HSA-9010553Reactome: R-HSA-9633012Reactome: R-HSA-9735869Reactome: R-HSA-9754678Reactome: R-HSA-975956Reactome: R-HSA-975957 |
Cellular Localisation | Cell MembraneCytoplasmNucleus67lr Is Found At The Surface Of The Plasma MembraneWith Its C-Terminal Laminin-Binding Domain Accessible To Extracellular Ligands37lrp Is Found At The Cell SurfaceIn The Cytoplasm And In The NucleusColocalizes With Ppp1r16b In The Cell Membrane |
Alternative Antibody Names | Anti-Small Ribosomal Subunit Protein Us2 antibodyAnti-37 Kda Laminin Receptor Precursor antibodyAnti-37lrp antibodyAnti-37/67 Kda Laminin Receptor antibodyAnti-Lrp/Lr antibodyAnti-40s Ribosomal Protein Sa antibodyAnti-67 Kda Laminin Receptor antibodyAnti-67lr antibodyAnti-Colon Carcinoma Laminin-Binding Protein antibodyAnti-Laminin Receptor 1 antibodyAnti-Lamr antibodyAnti-Laminin-Binding Protein Precursor P40 antibodyAnti-Lbp/P40 antibodyAnti-Multidrug Resistance-Associated Protein Mgr1-Ag antibodyAnti-Nem/1chd4 antibodyAnti-RPSA antibodyAnti-LAMBR antibodyAnti-LAMR1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance