| Host: |
Rabbit |
| Applications: |
IHC-P/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
COL15A1 |
| Gene ID: |
1306 |
| Uniprot ID: |
COFA1_HUMAN |
| Immunogen Region: |
200-450 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 200-450 of human COL15A1 (NP_001846.3). |
| Immunogen Sequence: |
AGIFMGNAGATGLERFTGSL QQLTVHPDPRTPEELCDPEE SSASGETSGLQEADGVAEIL EAVTYTQASPKEAKVEPINT PPTPSSPFEDMELSGEPVPE GTLETTNMSIIQHSSPKQGS GEILNDTLEGVHSVDGDPIT DSGSGAGAFLDIAEEKNLAA TAAGLAEVPISTAGEAEASS VPTGGPTLSMSTENPEEGVT PGPDNEERLAATAAGEAEAL ASMPGEVEASGVAPGELDL |
| Tissue Specificity | Detected in fibroblasts and urine (at protein level). Detected in placenta (at protein level). Expressed predominantly in internal organs such as adrenal gland, pancreas and kidney. |
| Post Translational Modifications | Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. O-glycosylated.with core 1 or possibly core 8 glycans. Contains chondroitin sulfate. |
| Function | Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle. Restin potently inhibits angiogenesis. |
| Protein Name | Collagen Alpha-1(Xv Chain Cleaved Into - RestinEndostatin-XvRelated To EndostatinRestin-I - Restin-2Restin-Ii - Restin-3Restin-Iii - Restin-4Restin-Iv |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1650814Reactome: R-HSA-2022090Reactome: R-HSA-8948216 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Collagen Alpha-1(Xv Chain Cleaved Into - Restin antibodyAnti-Endostatin-Xv antibodyAnti-Related To Endostatin antibodyAnti-Restin-I - Restin-2 antibodyAnti-Restin-Ii - Restin-3 antibodyAnti-Restin-Iii - Restin-4 antibodyAnti-Restin-Iv antibodyAnti-COL15A1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
