| Tissue Specificity | Detected in fibroblasts and urine (at protein level). Detected in placenta (at protein level). Expressed predominantly in internal organs such as adrenal gland, pancreas and kidney. |
| Post Translational Modifications | Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. O-glycosylated.with core 1 or possibly core 8 glycans. Contains chondroitin sulfate. |
| Function | Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle. Restin potently inhibits angiogenesis. |
| Protein Name | Collagen Alpha-1(Xv Chain Cleaved Into - RestinEndostatin-XvRelated To EndostatinRestin-I - Restin-2Restin-Ii - Restin-3Restin-Iii - Restin-4Restin-Iv |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1650814Reactome: R-HSA-2022090Reactome: R-HSA-8948216 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Collagen Alpha-1(Xv Chain Cleaved Into - Restin antibodyAnti-Endostatin-Xv antibodyAnti-Related To Endostatin antibodyAnti-Restin-I - Restin-2 antibodyAnti-Restin-Ii - Restin-3 antibodyAnti-Restin-Iii - Restin-4 antibodyAnti-Restin-Iv antibodyAnti-COL15A1 antibody |
Information sourced from Uniprot.org
