| Host: |
Rabbit |
| Applications: |
IF/ICC/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
COL14A1 |
| Gene ID: |
7373 |
| Uniprot ID: |
COEA1_HUMAN |
| Immunogen Region: |
1060-1360 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1060-1360 of human COL14A1 (NP_066933.1). |
| Immunogen Sequence: |
GALNKIGTDGTQVAMVQFTD DPRTEFKLNAYKTKETLLDA IKHISYKGGNTKTGKAIKYV RDTLFTAESGTRRGIPKVIV VITDGRSQDDVNKISREMQL DGYSIFAIGVADADYSELVS IGSKPSARHVFFVDDFDAFK KIEDELITFVCETASATCPV VHKDGIDLAGFKMMEMFGLV EKDFSSVEGVSMEPGTFNVF PCYQLHKDALVSQPTRYLHP EGLPSDYTISFLFRILPDT |
| Post Translational Modifications | Lysines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in all cases and bind carbohydrates. Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. May contain numerous cysteine residues involved in inter- and intramolecular disulfide bonding. |
| Function | Plays an adhesive role by integrating collagen bundles. It is probably associated with the surface of interstitial collagen fibrils via COL1. The COL2 domain may then serve as a rigid arm which sticks out from the fibril and protrudes the large N-terminal globular domain into the extracellular space, where it might interact with other matrix molecules or cell surface receptors. |
| Protein Name | Collagen Alpha-1(Xiv ChainUndulin |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1650814Reactome: R-HSA-2022090Reactome: R-HSA-8948216 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Collagen Alpha-1(Xiv Chain antibodyAnti-Undulin antibodyAnti-COL14A1 antibodyAnti-UND antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
