| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-CNTNAP2 (ECD) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | CNTNAP2 |
| Gene ID: | 26047 |
| Uniprot ID: | CNTP2_HUMAN |
| Immunogen Region: | ECD |
| Specificity: | Specific for CNTNAP2. |
| Immunogen: | A synthetic peptide from extracellular domain of human Contactin associated protein like 2 (CNTNAP2) conjugated to blue carrier protein was used as the antigen. |
| Function | Required for gap junction formation (Probable). Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the juxtaparanodal region of the axo-glial junction. |
| Protein Name | Contactin-Associated Protein-Like 2Cell Recognition Molecule Caspr2 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell ProjectionAxonCell JunctionParanodal Septate JunctionExpressed In The Juxtaparadonal Region |
| Alternative Antibody Names | Anti-Contactin-Associated Protein-Like 2 antibodyAnti-Cell Recognition Molecule Caspr2 antibodyAnti-CNTNAP2 antibodyAnti-CASPR2 antibodyAnti-KIAA0868 antibody |
Information sourced from Uniprot.org