Anti-CNTNAP1 antibody (STJ190723)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Contactin-associated protein 1 for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CNTNAP1 |
| Gene ID | 8506 |
| Uniprot ID | CNTP1_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | CNTP1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells. |
| Protein Name | Contactin-Associated Protein 1CasprCaspr1Neurexin IvNeurexin-4P190 |
| Database Links | Reactome: R-HSA-447043 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell JunctionParanodal Septate Junction |
| Alternative Antibody Names | Anti-Contactin-Associated Protein 1 antibodyAnti-Caspr antibodyAnti-Caspr1 antibodyAnti-Neurexin Iv antibodyAnti-Neurexin-4 antibodyAnti-P190 antibodyAnti-CNTNAP1 antibodyAnti-CASPR antibodyAnti-NRXN4 antibody |
Information sourced from Uniprot.org