Host: |
Goat |
Applications: |
Pep-ELISA/WB |
Reactivity: |
Human/Mouse/Rat/Dog |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Goat polyclonal antibody anti-CNTFR (Internal) is suitable for use in ELISA and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: |
0.5 mg/mL |
Dilution Range: |
WB-0.3-1µg/mlELISA-antibody detection limit dilution 1:16000. |
Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: |
CNTFR |
Gene ID: |
1271 |
Uniprot ID: |
CNTFR_HUMAN |
Immunogen Region: |
Internal |
Accession Number: |
NP_671693.1; NP_001833.1 |
Specificity: |
This antibody is expected to recognise both reported isoforms (NP_671693.1; NP_001833.1). |
Immunogen Sequence: |
CRSNTYPKGFY |
Function | Binds to CNTF. The alpha subunit provides the receptor specificity. Receptor for heterodimeric neurotropic cytokine composed of CLCF1/CLC and CRLF1/CLF-1. Acts as a receptor for the neuroprotective peptide humanin as part of a complex with IL6ST/GP130 and IL27RA/WSX1. |
Protein Name | Ciliary Neurotrophic Factor Receptor Subunit AlphaCntf Receptor Subunit AlphaCntfr-Alpha |
Database Links | Reactome: R-HSA-6788467 |
Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
Alternative Antibody Names | Anti-Ciliary Neurotrophic Factor Receptor Subunit Alpha antibodyAnti-Cntf Receptor Subunit Alpha antibodyAnti-Cntfr-Alpha antibodyAnti-CNTFR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance