| Host: | Mouse |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Calponin-1 (100-200 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Monoclonal |
| Clone ID : | ABT133 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2ak |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: | IHC-P 1:100-500 WB 1:200-1000 IF 1:100-500 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CNN1 |
| Gene ID: | 1264 |
| Uniprot ID: | CNN1_HUMAN |
| Immunogen Region: | 100-200 aa |
| Specificity: | The antibody can specifically recognize human and mouse calponin-1 protein. In western blotting of Hela, LnCap and mouse muscle lysates, the antibody can label a 34KDa band corresponding to calponin- |
| Immunogen: | Synthesized peptide derived from the human Calponin-1 at the amino acid range 100-200 |
| Function | Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. |
| Protein Name | Calponin-1 Basic Calponin Calponin H1 - Smooth Muscle |
| Alternative Antibody Names | Anti-Calponin-1 antibody Anti-Basic Calponin antibody Anti-Calponin H1 - Smooth Muscle antibody Anti-CNN1 antibody |
Information sourced from Uniprot.org