Anti-CNIH2 antibody (10-60 aa) (STJ195561)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human CNIH2 at the amino acid range 10-60
General Information
| Short Description | Rabbit polyclonal anti-Protein cornichon homolog 2 (10-60 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CNIH2 |
| Gene ID | 254263 |
| Uniprot ID | CNIH2_HUMAN |
| Immunogen | Synthesized peptide derived from the human CNIH2 at the amino acid range 10-60 |
| Immunogen Region | 10-60 aa |
| Specificity | This antibody detects endogenous levels of CNIH2 at Human/Mouse/Rat |
Additional Info
| Function | Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. Blocks CACNG8-mediated resensitization of AMPA receptors. |
| Protein Name | Protein Cornichon Homolog 2Cnih-2Cornichon Family Ampa Receptor Auxiliary Protein 2Cornichon-Like Protein |
| Database Links | Reactome: R-HSA-204005Reactome: R-HSA-5694530 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinPostsynaptic Cell MembraneCell ProjectionDendriteDendritic SpinePostsynaptic DensityAlso Localizes To The Cell Membrane Of Extrasynaptic Sites (Dendritic ShaftsSpines Of Pyramidal Cells) |
| Alternative Antibody Names | Anti-Protein Cornichon Homolog 2 antibodyAnti-Cnih-2 antibodyAnti-Cornichon Family Ampa Receptor Auxiliary Protein 2 antibodyAnti-Cornichon-Like Protein antibodyAnti-CNIH2 antibodyAnti-CNIL antibody |
Information sourced from Uniprot.org