Anti-CNDP2 antibody (1-210) (STJ112417)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CNDP2 (1-210) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CNDP2 |
| Gene ID | 55748 |
| Uniprot ID | CNDP2_HUMAN |
| Immunogen Region | 1-210 |
| Immunogen Sequence | MAALTTLFKYIDENQDRYIK KLAKWVAIQSVSAWPEKRGE IRRMMEVAAADVKQLGGSVE LVDIGKQKLPDGSEIPLPPI LLGRLGSDPQKKTVCIYGHL DVQPAALEDGWDSEPFTLVE RDGKLYGRGSTDDKGPVAGW INALEAYQKTGQEIPVNVRF CLEGMEESGSEGLDELIFAR KDTFFKDVDYVCISDNYWLG KKKPCITYGL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human CNDP2 (NP_060705.2). |
Additional Info
| Tissue Specificity | Isoform 1: Ubiquitously expressed with higher levels in kidney and liver (at protein level). Expressed in peripheral blood leukocytes. Expressed in gastric mucosa and down-regulated in gastric cancer mucosal tissues (at protein level). Isoform 2: Broadly expressed in fetal tissues. Expressed in adult liver and placenta. |
| Function | Catalyzes the peptide bond hydrolysis in dipeptides, displaying a non-redundant activity toward threonyl dipeptides. Mediates threonyl dipeptide catabolism in a tissue-specific way. Has high dipeptidase activity toward cysteinylglycine, an intermediate metabolite in glutathione metabolism. Metabolizes N-lactoyl-amino acids, both through hydrolysis to form lactic acid and amino acids, as well as through their formation by reverse proteolysis. Plays a role in the regulation of cell cycle arrest and apoptosis. |
| Protein Name | Cytosolic Non-Specific DipeptidaseCndp Dipeptidase 2Glutamate Carboxypeptidase-Like Protein 1Peptidase AThreonyl Dipeptidase |
| Database Links | Reactome: R-HSA-174403Reactome: R-HSA-9753281 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Cytosolic Non-Specific Dipeptidase antibodyAnti-Cndp Dipeptidase 2 antibodyAnti-Glutamate Carboxypeptidase-Like Protein 1 antibodyAnti-Peptidase A antibodyAnti-Threonyl Dipeptidase antibodyAnti-CNDP2 antibodyAnti-CN2 antibodyAnti-CPGL antibodyAnti-HEL-S-13 antibodyAnti-PEPA antibody |
Information sourced from Uniprot.org