| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CMAS |
| Gene ID: | 55907 |
| Uniprot ID: | NEUA_HUMAN |
| Immunogen Region: | 1-263 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-263 of human CMAS (NP_061156.1). |
| Immunogen Sequence: | MDSVEKGAATSVSNPRGRPS RGRPPKLQRNSRGGQGRGVE KPPHLAALILARGGSKGIPL KNIKHLAGVPLIGWVLRAAL DSGAFQSVWVSTDHDEIENV AKQFGAQVHRRSSEVSKDSS TSLDAIIEFLNYHNEVDIVG NIQATSPCLHPTDLQKVAEM IREEGYDSVFSVVRRHQFRW SEIQKGVREVTEPLNLNPAK RPRRQDWDGELYENGSFYFA KRHLIEMGYLQGGKMAYYE |
| Tissue Specificity | Ubiquitously expressed. Expressed in pancreas, kidney, liver, skeletal muscle, lung, placenta, brain, heart, colon, PBL, small intestine, ovary, testis, prostate, thymus and spleen. |
| Function | Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN). |
| Protein Name | N-Acylneuraminate CytidylyltransferaseCmp-N-Acetylneuraminic Acid SynthaseCmp-Neunac Synthase |
| Database Links | Reactome: R-HSA-4085001 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-N-Acylneuraminate Cytidylyltransferase antibodyAnti-Cmp-N-Acetylneuraminic Acid Synthase antibodyAnti-Cmp-Neunac Synthase antibodyAnti-CMAS antibody |
Information sourced from Uniprot.org