| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
CLPTM1L |
| Gene ID: |
81037 |
| Uniprot ID: |
CLP1L_HUMAN |
| Immunogen Region: |
32-280 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 32-280 of human CLPTM1L (NP_110409.2). |
| Immunogen Sequence: |
YTRPCSGDANCIQPYLARRP KLQLSVYTTTRSHLGAENNI DLVLNVEDFDVESKFERTVN VSVPKKTRNNGTLYAYIFLH HAGVLPWHDGKQVHLVSPLT TYMVPKPEEINLLTGESDTQ QIEAEKKPTSALDEPVSHWR PRLALNVMADNFVFDGSSLP ADVHRYMKMIQLGKTVHYLP ILFIDQLSNRVKDLMVINRS TTELPLTVSYDKVSLGRLRF WIHMQDAVYSLQQFGFSEK |
| Tissue Specificity | Ubiquitously expressed. |
| Function | Scramblase that mediates the translocation of glucosaminylphosphatidylinositol (alpha-D-GlcN-(1-6)-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol, GlcN-PI) across the endoplasmic reticulum (ER) membrane, from the cytosolic leaflet to the luminal leaflet of the ER membrane, where it participates in the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is a lipid glycoconjugate involved in post-translational modification of proteins. Can also translocate 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) (phosphatidylinositol or PI), as well as several other phospholipids (1,2-diacyl-sn-glycero-3-phosphocholine, 1,2-diacyl-sn-glycero-3-phosphoethanolamine), and N-acetylglucosaminylphosphatidylinositol (GlcNAc-PI) in vitro. |
| Protein Name | Lipid Scramblase Clptm1lCisplatin Resistance-Related Protein 9Crr9pCleft Lip And Palate Transmembrane Protein 1-Like ProteinClptm1-Like Protein |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Lipid Scramblase Clptm1l antibodyAnti-Cisplatin Resistance-Related Protein 9 antibodyAnti-Crr9p antibodyAnti-Cleft Lip And Palate Transmembrane Protein 1-Like Protein antibodyAnti-Clptm1-Like Protein antibodyAnti-CLPTM1L antibodyAnti-CRR9 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
