• Western blot analysis of the lysates from HeLa cells using CLIC4 antibody.
  • Western blot analysis of lysates from HT-29 cells, using CLIC4 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of HT29 cells using CLIC4 Polyclonal Antibody diluted at 1：1000
  • Immunohistochemistry analysis of paraffin-embedded human lymph node tissue, using CLIC4 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using CLIC4 Polyclonal Antibody diluted at 1：1000

Anti-CLIC4 antibody (1-50 aa) (STJ92330)

SKU:
STJ92330

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Chloride intracellular channel protein 4 (1-50 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CLIC4
Gene ID: 25932
Uniprot ID: CLIC4_HUMAN
Immunogen Region: 1-50 aa
Specificity: CLIC4 Polyclonal Antibody detects endogenous levels of CLIC4 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human CLIC4 at the amino acid range 1-50
Function Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis (tubulogenesis).
Protein Name Chloride Intracellular Channel Protein 4
Intracellular Chloride Ion Channel Protein P64h1
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Cytoplasmic Vesicle Membrane
Single-Pass Membrane Protein
Nucleus
Cell Membrane
Mitochondrion
Cell Junction
Colocalized With Akap9 At The Centrosome And Midbody
Exists Both As Soluble Cytoplasmic Protein And As Membrane Protein With Probably A Single Transmembrane Domain
Present In An Intracellular Vesicular Compartment That Likely Represent Trans-Golgi Network Vesicles
Might Not Be Present In The Nucleus Of Cardiac Cells
Alternative Antibody Names Anti-Chloride Intracellular Channel Protein 4 antibody
Anti-Intracellular Chloride Ion Channel Protein P64h1 antibody
Anti-CLIC4 antibody

Information sourced from Uniprot.org

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