• Western blot analysis of the lysates from HeLa cells using CLIC4 antibody.
  • Western blot analysis of lysates from HT-29 cells, using CLIC4 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of HT29 cells using CLIC4 Polyclonal Antibody diluted at 1：1000
  • Immunohistochemistry analysis of paraffin-embedded human lymph node tissue, using CLIC4 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using CLIC4 Polyclonal Antibody diluted at 1：1000

Anti-CLIC4 antibody (1-50 aa) (STJ92330)

SKU:
STJ92330

£48.00 - £252.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Chloride intracellular channel protein 4 (1-50 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CLIC4
Gene ID: 25932
Uniprot ID: CLIC4_HUMAN
Immunogen Region: 1-50 aa
Specificity: CLIC4 Polyclonal Antibody detects endogenous levels of CLIC4 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human CLIC4 at the amino acid range 1-50
Function In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor. Can insert into membranes and form voltage-dependent multi-ion conductive channels. Membrane insertion seems to be redox-regulated and may occur only under oxidizing conditions. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis (tubulogenesis). Promotes cell-surface expression of HRH3.
Protein Name Chloride Intracellular Channel Protein 4
Glutaredoxin-Like Oxidoreductase Clic4
Intracellular Chloride Ion Channel Protein P64h1
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Cytoplasmic Vesicle Membrane
Single-Pass Membrane Protein
Nucleus
Cell Membrane
Mitochondrion
Cell Junction
Endoplasmic Reticulum Membrane
Colocalized With Akap9 At The Centrosome And Midbody
Exists Both As Soluble Cytoplasmic Protein And As Membrane Protein With Probably A Single Transmembrane Domain
Present In An Intracellular Vesicular Compartment That Likely Represent Trans-Golgi Network Vesicles
Might Not Be Present In The Nucleus Of Cardiac Cells
Alternative Antibody Names Anti-Chloride Intracellular Channel Protein 4 antibody
Anti-Glutaredoxin-Like Oxidoreductase Clic4 antibody
Anti-Intracellular Chloride Ion Channel Protein P64h1 antibody
Anti-CLIC4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance