Tissue Specificity | In peripheral blood highly restricted on the surface of BDCA31(+) dendritic cells and on a small subset of CD14(+) and CD16(-) monocytes. |
Post Translational Modifications | N-glycosylated. |
Function | Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner. |
Protein Name | C-Type Lectin Domain Family 9 Member ACd Antigen Cd370 |
Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
Alternative Antibody Names | Anti-C-Type Lectin Domain Family 9 Member A antibodyAnti-Cd Antigen Cd370 antibodyAnti-CLEC9A antibodyAnti-UNQ9341 antibodyAnti-PRO34046 antibody |
Information sourced from Uniprot.org