Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-CLEC5A antibody (STJ192257)

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STJ192257
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-C-type lectin domain family 5 member A for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/ELISA
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
ELISA 1:5000-20000
Formulation:Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:CLEC5A
Gene ID:23601
Uniprot ID:CLC5A_HUMAN
Immunogen:Synthesized peptide derived from part of the human protein
Specificity:CLC5A Polyclonal Antibody detects endogenous levels of protein.
Post Translational Modifications N-glycosylated. Contains sialic acid residues.
Function Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. (Microbial infection) Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through the phosphorylation of TYROBP. This interaction does not result in viral entry, but stimulates pro-inflammatory cytokine release.
Protein Name C-Type Lectin Domain Family 5 Member A
C-Type Lectin Superfamily Member 5
Myeloid Dap12-Associating Lectin 1
Mdl-1
Database Links Reactome: R-HSA-2172127
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-C-Type Lectin Domain Family 5 Member A antibody
Anti-C-Type Lectin Superfamily Member 5 antibody
Anti-Myeloid Dap12-Associating Lectin 1 antibody
Anti-Mdl-1 antibody
Anti-CLEC5A antibody
Anti-CLECSF5 antibody
Anti-MDL1 antibody

Information sourced from Uniprot.org

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