Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Cleaved-Coagulation factor IX-Val227, Heavy Chain (226-227) is suitable for use in Western Blot and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:1000-2000ELISA 1:5000-20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
F9 |
Gene ID: |
2158 |
Uniprot ID: |
FA9_HUMAN |
Immunogen Region: |
226-227 |
Specificity: |
This antibody detects endogenous levels of Human, Mouse, Rat FA9 (heavy chain, Cleaved-Val227, protein was cleaved amino acid sequence between 226-227 ) |
Immunogen: |
Synthesized peptide derived from human FA9 (heavy chain, Cleaved-Val227) |
Tissue Specificity | Detected in blood plasma (at protein level). Synthesized primarily in the liver and secreted in plasma. |
Post Translational Modifications | Activated by factor XIa, which excises the activation peptide. The propeptide can also be removed by snake venom protease. The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains. |
Function | Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa. |
Protein Name | Coagulation Factor IxChristmas FactorPlasma Thromboplastin ComponentPtc Cleaved Into - Coagulation Factor Ixa Light Chain - Coagulation Factor Ixa Heavy Chain |
Database Links | Reactome: R-HSA-140834Reactome: R-HSA-140837Reactome: R-HSA-159740Reactome: R-HSA-159763Reactome: R-HSA-159782Reactome: R-HSA-9672383Reactome: R-HSA-9672396Reactome: R-HSA-9673202Reactome: R-HSA-9673218Reactome: R-HSA-9673221Reactome: R-HSA-9673240 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Coagulation Factor Ix antibodyAnti-Christmas Factor antibodyAnti-Plasma Thromboplastin Component antibodyAnti-Ptc Cleaved Into - Coagulation Factor Ixa Light Chain - Coagulation Factor Ixa Heavy Chain antibodyAnti-F9 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance