Anti-Cleaved-EFNA4-S170 antibody (170-171) (STJA0005860)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human Cleaved-Ephrin-A4 (S170)
General Information
| Short Description | Rabbit polyclonal anti-Cleaved-Ephrin-A4-S170 (170-171) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Dilution Range | WB 1:1000-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EFNA4 |
| Gene ID | 1945 |
| Uniprot ID | EFNA4_HUMAN |
| Immunogen | Synthesized peptide derived from human Cleaved-Ephrin-A4 (S170) |
| Immunogen Region | 170-171 |
| Specificity | This antibody detects endogenous levels of Human, Mouse Cleaved-Ephrin-A4 (S170, protein was cleaved amino acid sequence between 170-171 ) |
Additional Info
| Tissue Specificity | Expressed in the adult spleen, lymph node, prostate, ovary, small intestine, and colon, and in fetal heart, lung, liver and kidney. Also detected in hematopoietic cell lines. |
| Function | Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. May play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils. |
| Protein Name | Ephrin-A4Eph-Related Receptor Tyrosine Kinase Ligand 4Lerk-4 |
| Database Links | Reactome: R-HSA-2682334Reactome: R-HSA-3928663Reactome: R-HSA-3928665 |
| Cellular Localisation | Isoform 1: Cell MembraneLipid-AnchorGpi-AnchorIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Ephrin-A4 antibodyAnti-Eph-Related Receptor Tyrosine Kinase Ligand 4 antibodyAnti-Lerk-4 antibodyAnti-EFNA4 antibodyAnti-EPLG4 antibodyAnti-LERK4 antibody |
Information sourced from Uniprot.org